Estradiol Valerate 2mg Estradiol Valerate is an estrogen hormone used to manage estrogen deficiency symptoms in women. It helps in the treatment of menopausal symptoms (hot flashes, vaginal dryness, night sweats), menstrual irregularities, hypoestrogenism, and as part of hormone replacement therapy (HRT). It also supports bone health and prevents postmenopausal osteoporosis.