Description
Mebeverine Hydrochloride 135 mcg + Ispaghula Husk 3.5 mcg
Dosage Form: Oral Sachet
Pack Size: 10 × 5 GM
Manufacturer: Sarian Healthcare
Composition
MEBOLINE-I SACHET contains:
- Mebeverine Hydrochloride IP – 135 mcg per sachet
- Ispaghula Husk IP – 3.5 mcg per sachet
This combination brings together an intestinal antispasmodic and a bulk-forming fibre preparation. Mebeverine Hydrochloride acts directly on intestinal smooth muscle to help relieve gastrointestinal spasms and cramping, while Ispaghula Husk absorbs water and increases stool bulk to support bowel regularity.
Note: The strengths above are reproduced from the supplied product composition. The product label should be followed for the authoritative composition and administration instructions.
What Is MEBOLINE-I SACHET Used For?
MEBOLINE-I SACHET is a gastrointestinal combination containing Mebeverine Hydrochloride and Ispaghula Husk.
Mebeverine Hydrochloride is primarily used for symptomatic relief of intestinal smooth-muscle spasms and associated abdominal cramping. Ispaghula Husk is a bulk-forming fibre that absorbs water and increases stool bulk, supporting more regular bowel movements.
The combination may be clinically relevant in gastrointestinal conditions where intestinal spasms and altered bowel habits, particularly constipation-associated symptoms, occur together.
The exact indication should be established by the treating physician according to the patient’s symptoms, diagnosis, and overall treatment plan.
Key Ingredients and Their Functions
Mebeverine Hydrochloride 135 mcg
Drug Class: Gastrointestinal antispasmodic
Therapeutic Category: Gastrointestinal symptomatic therapy
Mebeverine Hydrochloride acts directly on intestinal smooth muscle and helps reduce excessive or abnormal intestinal contraction.
Primary Function:
Helps relieve intestinal smooth-muscle spasms and associated abdominal cramping.
Pharmacological Role:
Acts directly on intestinal smooth muscle to reduce excessive contraction and spasm without acting as a conventional anticholinergic antispasmodic.
Ispaghula Husk 3.5 mcg
Drug Class: Bulk-forming fibre / laxative
Therapeutic Category: Bowel-regulating therapy
Ispaghula Husk is a soluble, bulk-forming fibre that absorbs water within the gastrointestinal tract.
Primary Function:
Increases stool bulk and supports bowel regularity.
Pharmacological Role:
Forms a hydrated, gel-like mass within the gastrointestinal tract, helping influence stool consistency and facilitate bowel movement.
Adequate fluid intake is important when using bulk-forming fibre preparations.
Key Benefits of MEBOLINE-I SACHET
- Helps relieve intestinal spasms – Mebeverine Hydrochloride acts directly on intestinal smooth muscle to reduce spasm-related discomfort.
- Supports bowel regularity – Ispaghula Husk absorbs water and increases stool bulk, supporting normal bowel movement.
- Provides complementary gastrointestinal actions – Combines antispasmodic activity with fibre-based bowel regulation.
- Supports constipation-associated symptoms – Ispaghula Husk can help improve stool bulk and consistency when fibre supplementation is clinically appropriate.
- May help reduce cramping associated with intestinal spasm – Mebeverine provides targeted smooth-muscle antispasmodic activity.
- Convenient sachet dosage form – Supplied as a pre-packed oral sachet formulation for physician-directed gastrointestinal use.
How Does Mebeverine Hydrochloride 135 mcg + Ispaghula Husk 3.5 mcg Work?
MEBOLINE-I SACHET combines two different gastrointestinal mechanisms.
Action of Mebeverine Hydrochloride
Mebeverine Hydrochloride is a direct-acting intestinal antispasmodic. It acts on the smooth muscle of the gastrointestinal tract and reduces excessive or abnormal intestinal contraction.
By decreasing smooth-muscle spasm, Mebeverine can help relieve cramping and abdominal discomfort associated with intestinal spasm.
Action of Ispaghula Husk
Ispaghula Husk is a bulk-forming fibre. It absorbs water within the gastrointestinal tract and swells to form a hydrated, gel-like mass.
This increases stool bulk and can help improve stool consistency and facilitate bowel movement.
Adequate fluid intake is important when using Ispaghula-containing preparations.
Complementary Action
The combination provides complementary spasm-relieving and bowel-regulating activity.
Mebeverine primarily addresses intestinal smooth-muscle spasm, while Ispaghula Husk acts as a fibre-based stool regulator.
The clinical response depends on the underlying gastrointestinal disorder, bowel habits, hydration, diet, and individual patient factors.
Directions for Use
Use MEBOLINE-I SACHET orally according to the physician’s recommendation and product-label instructions.
- Prepare and administer the sachet according to the instructions supplied with the product.
- Ispaghula-containing preparations should be taken with adequate fluid as directed.
- Do not take the product dry unless specifically instructed by the product labeling.
- Maintain an appropriate fluid intake unless fluid restriction has been prescribed for a medical condition.
- The appropriate dose and frequency depend on the patient’s symptoms, age, diagnosis, and clinical response.
- Do not increase or reduce the dose independently.
- Do not use prolonged treatment for unexplained abdominal symptoms without medical evaluation.
- Separate administration from other oral medicines if advised by a healthcare professional, as bulk-forming fibre may affect the absorption of some medicines.
Dosage and treatment duration should be determined by the treating physician according to the patient’s clinical condition and response to therapy.
Possible Side Effects
Not every patient experiences side effects. Reactions may vary according to individual sensitivity, hydration, diet, dosage, and underlying gastrointestinal conditions.
Common or Possible Side Effects
- Abdominal bloating
- Flatulence
- Mild abdominal discomfort
- Nausea
- Changes in bowel habits
- Diarrhoea or constipation
- Abdominal fullness
Ispaghula Husk may initially increase gas or bloating as the gastrointestinal tract adapts to increased fibre intake.
Important Adverse Reactions
Rare hypersensitivity reactions can occur with Mebeverine, Ispaghula, or other formulation components.
Symptoms such as widespread rash, facial or throat swelling, difficulty breathing, or severe dizziness require urgent medical attention.
Insufficient fluid intake with bulk-forming fibre may increase the risk of gastrointestinal obstruction or impaction, particularly in susceptible individuals.
Severe or persistent abdominal pain, vomiting, marked abdominal distension, inability to pass stool or gas, rectal bleeding, or unexplained changes in bowel habits should be medically evaluated rather than managed with continued self-treatment.
Safety Information
Medical Supervision
Use MEBOLINE-I according to professional advice, particularly when abdominal symptoms are persistent, recurrent, severe, or unexplained.
Hypersensitivity
Avoid use in patients with known allergy to Mebeverine, Ispaghula/Psyllium, or any formulation component.
Intestinal Obstruction
Bulk-forming fibre should not be used when intestinal obstruction, ileus, or significant narrowing of the gastrointestinal tract is suspected.
Difficulty Swallowing
Patients with swallowing disorders should seek medical advice before using Ispaghula-containing preparations because inadequate fluid intake can increase the risk of obstruction.
Abdominal Symptoms
Do not use the product to mask severe abdominal pain without determining the underlying cause.
Hydration
Adequate fluid intake is important with Ispaghula Husk unless the physician has prescribed fluid restriction.
Pregnancy
Consult the treating physician before use during pregnancy.
Breastfeeding
Seek professional advice before use during lactation.
Pediatric Patients
Suitability and dosing should be established according to age and professional guidance. Do not extrapolate adult dosing to children.
Elderly Patients
Older adults should use the product according to professional advice, particularly when constipation, dehydration, swallowing difficulty, or multiple medicines are present.
Kidney Impairment
Patients with significant kidney disease or prescribed fluid restriction should discuss fibre and fluid requirements with their healthcare professional.
Liver Impairment
Inform the physician about significant liver disease before treatment.
Drug Interactions
Ispaghula Husk may affect the absorption of some orally administered medicines. Other medicines should be taken according to professional advice regarding appropriate timing.
Diabetes
Patients with diabetes should consider the fibre content and overall formulation as part of their treatment plan.
Driving
Mebeverine is not generally expected to impair driving ability, but patients should avoid driving if they experience dizziness or other symptoms that affect alertness.
Storage
Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children. Follow the storage instructions printed on the product packaging.
Storage Instructions
- Store in a cool, dry place.
- Keep away from direct sunlight and moisture.
- Keep out of reach of children.
- Follow the storage instructions printed on the product packaging.
- Keep the sachet properly sealed until use.
Sarian Healthcare – Pharmaceutical Company in Gujarat
Sarian Healthcare is a pharmaceutical company in Gujarat with a diverse portfolio of pharmaceutical products across multiple therapeutic categories and dosage forms.
MEBOLINE-I SACHET is part of Sarian Healthcare’s pharmaceutical product portfolio, combining Mebeverine Hydrochloride and Ispaghula Husk in a convenient oral sachet dosage form.
The company serves healthcare professionals, pharmaceutical distributors, stockists, pharmacies, hospitals, clinics, and pharmaceutical procurement teams.
Pharmaceutical Company in Ahmedabad and Changodar
Sarian Healthcare is part of the pharmaceutical ecosystem serving Ahmedabad, Changodar, and other pharmaceutical markets across Gujarat.
The company maintains a pharmaceutical product portfolio covering different therapeutic categories and dosage forms to support healthcare and pharmaceutical supply requirements.
Pharmaceutical Manufacturers in Gujarat
Gujarat is an established pharmaceutical manufacturing and supply hub in India.
Sarian Healthcare contributes to this pharmaceutical ecosystem through its portfolio of pharmaceutical formulations and healthcare products, supporting professional healthcare and pharmaceutical supply channels.
Generic Medicine Company in Gujarat
Sarian Healthcare maintains a broad pharmaceutical portfolio designed to support healthcare requirements across different therapeutic segments.
Its products are developed and supplied for professional healthcare use through appropriate pharmaceutical distribution and procurement channels.
Healthcare Companies in Ahmedabad
Ahmedabad and its surrounding industrial areas form an important part of Gujarat’s healthcare and pharmaceutical ecosystem.
Sarian Healthcare serves healthcare professionals, distributors, stockists, pharmacies, hospitals, clinics, and procurement teams through its pharmaceutical product portfolio.
Pharma Distributors and Wholesale Supply
MEBOLINE-I SACHET is part of Sarian Healthcare’s pharmaceutical product portfolio for professional healthcare and pharmaceutical supply channels.
Distributors, stockists, pharmacies, hospitals, clinics, and pharmaceutical procurement teams can contact Sarian Healthcare for product availability, commercial information, and supply-related enquiries.
For businesses searching for pharma distributors, pharmaceutical suppliers, or wholesale pharmaceutical products, Sarian Healthcare provides a structured pharmaceutical portfolio for professional procurement requirements.
Medicine Manufacturing Company in Ahmedabad
Sarian Healthcare is associated with the pharmaceutical manufacturing and supply ecosystem serving Ahmedabad and Gujarat.
Its product portfolio includes pharmaceutical formulations across multiple therapeutic categories and dosage forms, supporting the requirements of healthcare professionals and pharmaceutical distribution networks.
Why Choose Sarian Healthcare as a Reliable Pharmaceutical Partner?
Sarian Healthcare focuses on developing and maintaining a reliable pharmaceutical product portfolio supported by professional product development and supply practices.
Key aspects include:
- Diverse pharmaceutical portfolio across multiple therapeutic categories
- Multiple dosage forms for different healthcare requirements
- Quality-focused pharmaceutical processes
- Professional product information for healthcare and procurement teams
- Support for distributors and stockists
- Pharmaceutical supply across healthcare channels
- Focus on consistent product availability
- Growing presence within Gujarat’s pharmaceutical ecosystem
- Professional approach to pharmaceutical product development and distribution
For doctors, pharmacists, distributors, stockists, hospitals, clinics, and pharmaceutical procurement teams, Sarian Healthcare provides a portfolio designed to support professional healthcare supply requirements.
Sarian Healthcare – Growing Pharmaceutical Partner in India
Sarian Healthcare continues to expand its pharmaceutical product portfolio across multiple therapeutic areas and dosage forms.
The company’s focus on pharmaceutical products, supply capabilities, and professional healthcare partnerships supports its growing presence within India’s pharmaceutical sector.
With products such as MEBOLINE-I SACHET, Sarian Healthcare addresses gastrointestinal pharmaceutical requirements through a combination formulation containing Mebeverine Hydrochloride and Ispaghula Husk.
MEBOLINE-I SACHET – Product Summary
MEBOLINE-I SACHET contains Mebeverine Hydrochloride 135 mcg + Ispaghula Husk 3.5 mcg as supplied in the product composition.
Mebeverine Hydrochloride acts directly on intestinal smooth muscle to help relieve gastrointestinal spasms and cramping, while Ispaghula Husk absorbs water and increases stool bulk to support bowel regularity.
The product is supplied as a 10 × 5 GM oral sachet pack and is manufactured by Sarian Healthcare.
Its use, dosage, frequency, and treatment duration should be determined according to the patient’s condition, physician’s recommendation, and product labeling. Adequate fluid intake is particularly important when using Ispaghula-containing preparations.
