GLISOT 1-PM Tablets Glimepiride 1mg Pioglitazone 15mg and Metformin 500mg PR Antidiabetic Medicine by Sarian Healthcare

Glimepiride, Pioglitazone, Metformin | GLISOT 1 PM Tablets

₹1,150.00

Manages blood sugar by improving insulin sensitivity, increasing secretion, and decreasing sugar production.

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Product Specifications

Composition: Glimepiride 1mg | Pioglitazone 15mg & Metformin 500mg(PR)
Dosage Form: Tablets
Therapeutic Categories: Antidiabetics
SKU: GLISOT 1 PM Tablets Categories: , Tags: , , Brand:

Description

1. Description:

GLISOT 1-PM Tablets (Glimepiride & Pioglitazone & Metformin) is an advanced triple-combination antidiabetic formulation containing Glimepiride 1mg, Pioglitazone 15mg, and Metformin 500mg (Prolonged Release), designed for the comprehensive management of Type 2 Diabetes Mellitus. This synergistic oral antidiabetic therapy is recommended for patients who require enhanced glycemic control beyond dual-drug therapy.

The formulation combines three proven antidiabetic agents with complementary mechanisms of action. Glimepiride stimulates pancreatic insulin secretion, Pioglitazone improves insulin sensitivity, and Metformin PR reduces hepatic glucose production while enhancing peripheral glucose utilization. The prolonged-release Metformin technology ensures sustained blood sugar control with improved gastrointestinal tolerability and better patient adherence.

GLISOT 1-PM Tablets help control fasting and postprandial blood glucose levels while supporting long-term diabetes management and reducing the risk of diabetic complications such as neuropathy, nephropathy, retinopathy, and cardiovascular disorders. Manufactured under stringent WHO-GMP quality standards by Sarian Healthcare, this formulation is trusted by healthcare professionals, pharmacies, hospitals, and pharmaceutical distributors across India.


2. Key Ingredient: (Glimepiride & Pioglitazone & Metformin)

Glimepiride 1mg
Glimepiride is a third-generation sulfonylurea antidiabetic agent that stimulates the pancreas to release insulin, thereby helping lower elevated blood glucose levels.

Pioglitazone 15mg
Pioglitazone belongs to the thiazolidinedione class and improves insulin sensitivity in muscle and adipose tissues, enabling better glucose utilization by the body.

Metformin 500mg (PR)
Metformin Prolonged Release is a biguanide antidiabetic medicine that decreases glucose production in the liver and improves insulin sensitivity while offering sustained glycemic control and improved gastrointestinal tolerance.

3. Key Benefits:
Provides comprehensive triple-action blood sugar management
Helps effectively control fasting and post-meal glucose levels
Improves insulin secretion and insulin sensitivity simultaneously
Sustained-release Metformin ensures prolonged glycemic control
Helps reduce the risk of diabetes-related complications
Convenient oral therapy enhances patient compliance and adherence

4. How Does It Work?
GLISOT 1-PM Tablets (Glimepiride & Pioglitazone & Metformin) work through multiple complementary mechanisms. Glimepiride stimulates pancreatic beta cells to increase insulin release. Pioglitazone enhances insulin sensitivity in peripheral tissues, improving glucose utilization. Metformin PR decreases hepatic glucose production and improves insulin action. Together, these agents provide effective and sustained glycemic control in Type 2 Diabetes Mellitus.

5. Directions for Use:
Take GLISOT 1-PM Tablets (Glimepiride & Pioglitazone & Metformin) exactly as prescribed by the physician
Usually administered with meals to reduce gastrointestinal discomfort
Swallow the prolonged-release tablet whole with water
Do not crush, chew, or break the tablet
Maintain regular dosing timing for optimal therapeutic results
Follow recommended diabetic diet and exercise guidelines
Monitor blood glucose levels regularly during therapy
Do not discontinue treatment without medical advice

6. Possible Side Effects:
Common side effects may include:

Hypoglycemia (low blood sugar)
Nausea
Vomiting
Diarrhea
Stomach discomfort
Headache
Dizziness
Weight gain or fluid retention

Seek medical attention if symptoms persist or worsen.

7. Safety Information:
Use only under medical supervision
Not recommended for patients with Type 1 Diabetes Mellitus or diabetic ketoacidosis
Use cautiously in patients with kidney, liver, or heart disorders
Regular monitoring of blood glucose, liver function, and renal function is recommended
Avoid excessive alcohol consumption during treatment
Inform the physician about all current medications and medical history
Use during pregnancy and lactation only if prescribed by a healthcare professional
Store in a cool, dry place away from moisture and direct sunlight
Keep out of reach of children

8. For More Information:
For more information about GLISOT 1-PM Tablets (Glimepiride & Pioglitazone & Metformin) Click Here.

Additional information

Product Name

GLISOT 1 PM Tablets
Generic Name

Glimepiride, Pioglitazone, Metformin
Composition

Glimepiride 1mg, Pioglitazone 15mg & Metformin 500mg(PR)
Dosage Form

Therapeutic Categories

Drug Class

Sulfonylurea and Thiazolidinedione and Biguanide
Indication

Type 2 Diabetes Mellitus with insulin resistance
Target Infections - Conditions

Type 2 diabetes mellitus with insulin resistance
Strength

Glimepiride 1mg, Pioglitazone 15mg, Metformin 500mg
Pack Size

10*15 Tablets
Packaging Type

Blister
Storage Conditions

Store in a cool and dry place below 25?C. Protect from moisture and direct sunlight.
Prescription Status

Rx (To be taken under medical supervision)

Available In

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Product FAQ

1. What is GLISOT 1-PM Tablets used for?

GLISOT 1-PM Tablets are used for the treatment and management of Type 2 Diabetes Mellitus in patients requiring triple-drug antidiabetic therapy.

2. What are the active ingredients in GLISOT 1-PM?

The formulation contains Glimepiride 1mg, Pioglitazone 15mg, and Metformin 500mg Prolonged Release.

3. How does GLISOT 1-PM control blood sugar?

It increases insulin secretion, improves insulin sensitivity, and reduces glucose production in the liver for comprehensive glycemic management.

4. What is the advantage of Metformin PR in this formulation?

Metformin PR provides sustained glucose control with better gastrointestinal tolerability and improved patient compliance.

5. Can GLISOT 1-PM Tablets cause hypoglycemia?

Yes, low blood sugar may occur, especially if meals are skipped or dosage instructions are not followed properly.

6. Is GLISOT 1-PM suitable for long-term diabetes management?

Yes, it is commonly prescribed for long-term management of Type 2 Diabetes under medical supervision.

7. Can this medicine help reduce diabetic complications?

Effective blood sugar control may help reduce the risk of diabetes-related complications affecting the kidneys, nerves, eyes, and cardiovascular system.

8. Who should avoid GLISOT 1-PM Tablets?

Patients with severe kidney disease, liver dysfunction, heart failure, or hypersensitivity to the ingredients should avoid this medication unless advised otherwise by a physician.

9. Is regular blood glucose monitoring necessary?

Yes, regular monitoring helps evaluate treatment effectiveness and maintain optimal glycemic control.

10. Why choose Sarian Healthcare antidiabetic formulations?

Sarian Healthcare offers WHO-GMP certified pharmaceutical formulations with advanced manufacturing standards, reliable efficacy, and strong B2B pharma distribution support across India.

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