Description
BUDOWELL-L 500/1.25 RESPULES
Composition: Budesonide 0.5mg + Levosalbutamol 1.25mg per 2mL Respule
Pack Size: 8 × 5 × 2mL
Manufacturer: Sarian Healthcare
Budesonide 0.5mg + Levosalbutamol 1.25mg Respules
BUDOWELL-L 500/1.25 RESPULES contains Budesonide 0.5mg + Levosalbutamol 1.25mg in each 2mL respule. It is an inhaled combination of a corticosteroid and a short-acting bronchodilator used under medical supervision for respiratory conditions involving airway inflammation and bronchospasm.
Budesonide helps reduce inflammatory activity within the airways, while levosalbutamol provides bronchodilation by relaxing bronchial smooth muscle. The combination therefore provides complementary anti-inflammatory and airway-opening effects when both treatment approaches are clinically appropriate.
Budesonide belongs to the inhaled corticosteroid/glucocorticoid class and primarily acts on airway inflammation. Levosalbutamol, also known as levalbuterol, is a selective short-acting beta2-adrenergic receptor agonist that stimulates beta2 receptors in bronchial smooth muscle and promotes bronchodilation.
The clinical positioning of Budesonide + Levosalbutamol depends on the patient’s respiratory diagnosis, symptom pattern, treatment history, and physician assessment. It should not be assumed to be appropriate for every cause of breathlessness or cough.
For healthcare professionals, distributors, stockists, and procurement teams searching for a Budesonide 0.5mg + Levosalbutamol 1.25mg pharmaceutical product, Budesonide respules supplier, or respiratory medicine manufacturer, BUDOWELL-L 500/1.25 RESPULES is a Sarian Healthcare pharmaceutical product intended for physician-directed respiratory therapy and professional pharmaceutical sourcing requirements.
Composition
Budesonide 0.5mg
Active Ingredient: Budesonide
Strength: 0.5mg per 2mL respule
Drug Class: Inhaled corticosteroid / glucocorticoid
Therapeutic Category: Respiratory anti-inflammatory medicine
Primary Function: Reduction of airway inflammation
Budesonide activates glucocorticoid receptors and suppresses multiple inflammatory pathways involved in airway inflammation.
Levosalbutamol 1.25mg
Active Ingredient: Levosalbutamol (Levalbuterol)
Strength: 1.25mg per 2mL respule
Drug Class: Short-acting selective beta2-adrenergic receptor agonist (SABA)
Therapeutic Category: Bronchodilator
Primary Function: Relaxation of bronchial smooth muscle
Levosalbutamol stimulates beta2-adrenergic receptors, increases intracellular cyclic AMP, and produces bronchodilation.
What Is Budesonide + Levosalbutamol Used For?
Budesonide + Levosalbutamol combination therapy may be used under medical supervision for respiratory conditions involving airway inflammation and bronchospasm, where an inhaled corticosteroid together with a short-acting bronchodilator is clinically appropriate.
The two active ingredients address different aspects of airway symptoms:
- Budesonide helps reduce airway inflammation.
- Levosalbutamol helps relax bronchial smooth muscle and promote bronchodilation.
The appropriate clinical use depends on the patient’s respiratory diagnosis, symptoms, previous treatment, and physician’s assessment.
The combination should not automatically be considered appropriate for every cause of cough, wheezing, or breathlessness.
Key Ingredients and Their Functions
Budesonide
Budesonide is an inhaled glucocorticoid corticosteroid. It primarily works on inflammatory processes within the respiratory tract.
After reaching airway tissues, it interacts with intracellular glucocorticoid receptors and influences gene transcription involved in inflammation. This reduces the production and activity of multiple inflammatory mediators.
Levosalbutamol
Levosalbutamol, also known as levalbuterol, is a selective short-acting beta2-adrenergic receptor agonist.
It stimulates beta2 receptors on bronchial smooth muscle and increases intracellular cyclic AMP. This promotes relaxation of bronchial smooth muscle and produces bronchodilation.
Key Benefits of BUDOWELL-L 500/1.25 RESPULES
- Complementary respiratory action: Combines an inhaled corticosteroid with a short-acting bronchodilator.
- Airway inflammation control: Budesonide helps reduce inflammatory activity within the airways.
- Bronchodilation: Levosalbutamol promotes relaxation of bronchial smooth muscle and supports improved airflow.
- Nebulized administration: The 2mL respule format enables administration through an appropriate nebulization system when prescribed.
- Dual pharmacological pathway: The ingredients work through different mechanisms to provide complementary effects.
- Convenient combination formulation: A single respule contains both specified active ingredients for physician-directed respiratory management.
How Does Budesonide 0.5mg + Levosalbutamol 1.25mg Work?
BUDOWELL-L 500/1.25 RESPULES works through two complementary pharmacological mechanisms.
Action of Budesonide
Budesonide is an inhaled glucocorticoid. It enters airway cells and binds to intracellular glucocorticoid receptors.
This interaction influences gene transcription and reduces the production and activity of inflammatory mediators. The resulting anti-inflammatory activity helps reduce airway inflammation and related inflammatory changes.
Action of Levosalbutamol
Levosalbutamol is a selective short-acting beta2-adrenergic receptor agonist.
It binds to beta2 receptors on bronchial smooth muscle and activates adenylate cyclase, increasing intracellular cyclic AMP. This promotes relaxation of bronchial smooth muscle and produces bronchodilation.
Combined Action
Together, the two ingredients address two important components of obstructive airway symptoms:
Airway inflammation → Budesonide
Bronchoconstriction → Levosalbutamol
The exact therapeutic role of the combination depends on the patient’s clinical condition and physician-directed treatment plan.
Directions for Use
Use BUDOWELL-L 500/1.25 RESPULES only as prescribed by a qualified healthcare professional.
- The respule is intended for inhalation through an appropriate nebulization device.
- Do not swallow the respule contents.
- Do not use the product by injection.
- The exact dosage, frequency, nebulizer requirements, and treatment duration should be determined by the treating physician.
- Use the product according to the prescribed nebulization procedure and the manufacturer’s instructions for the nebulizer.
- Do not change the prescribed dose or frequency independently.
- Rinse the mouth after inhalation to help reduce the risk of oral candidiasis associated with inhaled corticosteroid therapy.
- If a face mask is used, ensure appropriate fitting and wash the face after treatment if medication deposits on the skin.
- Do not use additional doses for acute breathing symptoms unless specifically instructed by the physician.
- Do not discontinue prescribed corticosteroid-containing treatment without medical advice.
Dosage and treatment duration should be determined by the treating physician according to the patient’s clinical condition and response to therapy.
Possible Side Effects
Possible side effects associated with Budesonide + Levosalbutamol therapy may include:
- Headache
- Tremor
- Nervousness or restlessness
- Throat irritation
- Cough
- Hoarseness or voice changes
- Dry mouth
- Nausea
- Palpitations or increased awareness of heartbeat
- Muscle cramps
- Oral or throat candidiasis
Not every patient experiences these effects.
Important Adverse Reactions
Clinically important reactions may include:
- Paradoxical bronchospasm or worsening breathing immediately after inhalation
- Hypersensitivity reactions, including rash, swelling, or bronchospasm
- Significant tachycardia or cardiac rhythm disturbances
- Hypokalemia or other metabolic effects associated with beta2-agonist therapy
- Systemic corticosteroid effects with prolonged or substantial corticosteroid exposure
- Adrenal suppression
- Reduced bone mineral density with prolonged corticosteroid exposure
- Cataracts or glaucoma with long-term corticosteroid exposure
Severe breathing difficulty, facial or throat swelling, significant palpitations, or other serious symptoms require prompt medical attention.
Safety Information
Use Budesonide + Levosalbutamol only according to the prescribing physician’s instructions.
- Hypersensitivity: Avoid use in patients with a known allergy to budesonide, levosalbutamol, or any component of the formulation.
- Acute symptoms: The appropriate treatment for sudden severe bronchospasm should be determined by the treating clinician. Do not automatically rely on this combination as an emergency rescue treatment.
- Cardiovascular conditions: Levosalbutamol may cause cardiovascular effects. Patients with heart disease, arrhythmias, hypertension, or other cardiovascular disorders should inform their physician.
- Diabetes: Beta2-agonists may affect blood glucose levels in susceptible individuals.
- Electrolytes: Levosalbutamol can contribute to reduced serum potassium in susceptible patients, particularly when combined with other medicines affecting potassium.
- Thyroid disorders: Use cautiously in patients with hyperthyroidism or other thyroid disorders.
- Seizure disorders: Inform the physician about a history of seizures before treatment.
- Infections: Prolonged inhaled corticosteroid exposure may increase susceptibility to certain local or systemic infections.
- Kidney impairment: Patients with renal impairment should inform their physician so overall treatment can be appropriately assessed.
- Liver impairment: Severe hepatic impairment may affect corticosteroid exposure and should be medically supervised.
- Pregnancy: Use during pregnancy only when clinically indicated and under medical supervision.
- Breastfeeding: Consult the treating physician before using this combination during lactation.
- Pediatric patients: Pediatric use should be based on the specific formulation, indication, age, and physician’s assessment. Prolonged corticosteroid exposure may require monitoring of growth and other systemic effects.
- Elderly patients: Older patients may require monitoring for cardiovascular, metabolic, and corticosteroid-related effects.
- Drug interactions: Inform the physician about beta-blockers, other beta2-agonists, diuretics, corticosteroids, medicines affecting potassium, tricyclic antidepressants, monoamine oxidase inhibitors, and other regular medicines.
- Driving: If tremor, dizziness, palpitations, or other symptoms impair alertness or coordination, avoid driving or operating machinery until medically safe.
Storage Instructions
Store BUDOWELL-L 500/1.25 RESPULES in a cool, dry place away from direct sunlight and moisture.
Keep out of reach of children and follow the storage instructions printed on the product packaging.
Sarian Healthcare – Pharmaceutical Company in Gujarat
Sarian Healthcare is a pharmaceutical company in Gujarat serving professional healthcare and pharmaceutical supply requirements across multiple therapeutic segments.
The company’s pharmaceutical portfolio supports healthcare professionals, distributors, stockists, pharmacies, hospitals, clinics, and institutional procurement channels.
For businesses searching for a pharmaceutical company in Gujarat, Sarian Healthcare provides pharmaceutical products through professional healthcare supply channels.
Pharmaceutical Company in Ahmedabad and Changodar
Sarian Healthcare is part of Gujarat’s pharmaceutical ecosystem and supports professional pharmaceutical requirements in Ahmedabad, Changodar, and surrounding markets.
For businesses searching for a pharmaceutical company in Ahmedabad or pharma company in Changodar, Sarian Healthcare offers pharmaceutical products and professional supply support.
Pharmaceutical Manufacturers in Gujarat
Gujarat has a well-established pharmaceutical ecosystem encompassing pharmaceutical manufacturing, healthcare distribution, product supply, and related services.
Sarian Healthcare contributes to this ecosystem through its pharmaceutical product portfolio and professional supply channels.
For organizations searching for pharmaceutical manufacturers in Gujarat, Sarian Healthcare can be approached for product-related and pharmaceutical supply enquiries.
Generic Medicine Company in Gujarat
Sarian Healthcare maintains a growing pharmaceutical portfolio covering different therapeutic categories and healthcare requirements.
Businesses searching for a generic medicine company in Gujarat can connect with Sarian Healthcare regarding product availability, supply information, and professional pharmaceutical requirements.
Healthcare Companies in Ahmedabad
Sarian Healthcare is part of the healthcare and pharmaceutical business network serving Ahmedabad and surrounding markets.
The company supports professional requirements involving pharmaceutical distributors, stockists, pharmacies, healthcare institutions, and other authorized supply partners.
Pharma Distributors and Wholesale Supply
Sarian Healthcare supports pharmaceutical supply requirements for pharma distributors, stockists, wholesalers, pharmacies, hospitals, clinics, and healthcare institutions.
Businesses interested in BUDOWELL-L 500/1.25 RESPULES or other products from the Sarian Healthcare portfolio can contact the company for product availability, commercial information, and professional supply enquiries.
Medicine Manufacturing Company in Ahmedabad
For businesses searching for a medicine manufacturing company in Ahmedabad, Sarian Healthcare offers a growing pharmaceutical product portfolio across different therapeutic areas.
Its products support professional healthcare supply channels and pharmaceutical business requirements across relevant markets.
Why Choose Sarian Healthcare as a Reliable Pharmaceutical Partner?
Selecting a pharmaceutical partner involves considering product portfolio, supply support, professional communication, consistency, and market requirements.
Sarian Healthcare focuses on supporting healthcare and pharmaceutical businesses through:
- Diverse pharmaceutical portfolio across multiple therapeutic categories
- Professional pharmaceutical supply for distributors, stockists, pharmacies, hospitals, and healthcare institutions
- Quality-focused product operations
- Growing presence in Gujarat’s pharmaceutical ecosystem
- Support for pharmaceutical procurement requirements
- Professional product and business communication
- Distribution-oriented pharmaceutical supply support
- Respiratory product portfolio supporting professional healthcare requirements
Sarian Healthcare works with professional pharmaceutical supply partners to support product availability and evolving healthcare market requirements.
Sarian Healthcare – Growing Pharmaceutical Partner in India
Sarian Healthcare continues to develop its pharmaceutical portfolio across different therapeutic segments while supporting professional healthcare supply requirements.
Products such as BUDOWELL-L 500/1.25 RESPULES form part of its respiratory product portfolio, providing healthcare and pharmaceutical procurement channels with access to nebulized respiratory products.
For product enquiries, distributor and stockist requirements, institutional procurement, and pharmaceutical supply information, businesses can connect with Sarian Healthcare.
BUDOWELL-L 500/1.25 RESPULES – Product Summary
BUDOWELL-L 500/1.25 RESPULES contains Budesonide 0.5mg + Levosalbutamol 1.25mg per 2mL respule.
Budesonide provides inhaled corticosteroid anti-inflammatory activity, while levosalbutamol provides short-acting bronchodilator activity. The two ingredients work through complementary pharmacological mechanisms for physician-directed respiratory therapy where combination treatment is clinically appropriate.
Product: BUDOWELL-L 500/1.25 RESPULES
Composition: Budesonide 0.5mg + Levosalbutamol 1.25mg
Dosage Form: 2mL Respule
Pack Size: 8 × 5 × 2mL
Manufacturer: Sarian Healthcare









